2. Immunology/Inflammation
  3. CD3 CD20
  4. Epcoritamab

Epcoritamab  (Synonyms: 艾可瑞妥单抗; GEN3013)

目录号: HY-P99931 纯度: 99.84%
COA

摩尔计算器

Epcoritamab (GEN3013) 是一种双特异性 IgG1 抗体，可将 T 细胞重定向至 CD3×CD20+ 肿瘤细胞。

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CAS No. : 2134641-34-0

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规格 价格 是否有货 数量
1 mg ￥6500
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Epcoritamab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Epcoritamab (GEN3013) is an bispecific IgG1 antibody redirecting T-cells toward CD3×CD20+ tumor cells. Epcoritamab induces potent T-cell-mediated cytotoxicity towards B-cell NHL cell lines[1].

同型

Ig(G1-kappa_G1-lambda2)
种属

Human; Chimeric
体外研究
(In Vitro)

Epcoritamab (30 ng/mL) 在健康供体外周血单核细胞 (PBMC) 存在的情况下诱导有效的细胞毒性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Epcoritamab 相关抗体:
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

艾可瑞妥单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Ig(G1-kappa_G1-lambda2)
Biological Activity
  • Immobilized Human CD3 epsilon/CD3e Protein (ECD, His Tag) can bind Epcoritamab. The EC50 for this effect is 2.85 ng/mL.
纯度 & 产品资料
参考文献

Epcoritamab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Epcoritamab2134641-34-0GEN3013艾可瑞妥单抗GEN 3013GEN-3013CD3CD20Cluster of differentiation 3peripheral blood mononuclear cellsPBMCInhibitorinhibitorinhibit

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